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What is the preferred immunosuppressive modality for patients with an acquired factor 8 inhibitor?

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After control of active bleeding, how would you eliminate a Factor VIII inhibitor?

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1 Answer
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Hematology · Mount Sinai
Answered on

Classic steroids. If no response in a month, would consider cyclophosphamide.

A variety of immunosuppressive agents have been used. In Chapel Hill, they use rituximab, but a fair number of patients have relapses and older groups get infections. I typically use rituximab last.

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