What is the preferred number of cycles of CAPOX for rectal cancer receiving total neoadjuvant chemotherapy?
Answer from: Medical Oncologist at Community Practice
The treatment of rectal cancer is probably more confusing than ever before!The typical approach to “TNT” has been to give 4 months (8 cycles) of FOLFOX.The optimal duration of Capox is less defined.One reasonable option would be to aim for the same duration of 4 months. This would be ~5-...
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Answer from: Medical Oncologist at Academic Institution
As with Dr. @Steven J. Cohen's excellent advice, I aim for 6 cycles of CAPOX in neoadjuvant therapy for advanced rectal cancer that I am treating with a TNT approach.Similarly, I worry that we may be over-treating a not insignificant subset of patients with a universal TNT approach. As such, I ...
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Medical Oncologist at Ventura County Medical Center
In patients who received the TNT protocol and have...
In patients who received the TNT protocol and have...
Medical Oncologist at Oregon Health & Science University
I do not give any additional therapy in this situa...
I do not give any additional therapy in this situa...