What is the rationale behind the Anesthesiology recommendation to hold one dose of weekly GLP-RA prior to general anesthesia?

Topics: Diabetes • Endocrinology

There is a current recommendation from the anesthesia society to hold one dose of GLP-RA prior to general anesthesia. Given the long half-life of the once weekly GLP RAs, what is the rationale behind this recommendation since in most patients, the blood level should be the same on the day of surgery unless the medication were stopped at least 2 weeks before?

Answer from: at Academic Institution

There is evidence that people treated with GLP-1 receptor agonists (GLP-1RA) more often have residual food in the stomach after an overnight fast and greater gastric volume. There is anecdotal evidence of aspiration events in people treated with GLP-1RA. The ASA statement raises a concern and provid...

Comments

at Albert Einstein College of Medicine of Yeshiva University
When I reviewed the Anesthesia Society recommendat...

at Pinnaclehealth Endocrinology Associates
Endocrinologist or not, decreasing the true potent...

at Blum David A Office
I wonder if diabetic surgical patients with retain...

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