What is the recommended fungal workup in an immunocompromised patient after 5 days of persistent fever?

For any patient with fevers, I focus significantly on any symptoms that a patient might have, like headache, diarrhea, and sinus symptoms, and work up a differential diagnosis based on possible pathogens in this area. If I am not finding anything, I would obtain a CT chest/abd/pelvis, as both invasi...

CT chest at the very least, regardless of symptoms.

Serum galactomannan.

I tend to find BDG worthless/problematic.

It is important to obtain a CT chest despite a normal chest x-ray, including in patients with fever and with or without respiratory symptoms. It is not uncommon to see abnormal CT chest findings, with no resp symptoms/signs. Fever may be the only abnormality. In many cases, radiology is more reliabl...