Topics:
Radiation Oncology • Pediatric Oncology
What is the risk of secondary malignancy and/or conversion to MPNST for patients with NF-1 who undergo radiation?
Is it higher than the average person?
Answer from: Radiation Oncologist at Academic Institution
Broadly speaking, this is certainly a possibility and this has been a reason why the community has triaged the application of radiotherapy to more high-risk cases (Williams et al., PMID 19117870). Just playing out the numbers independent of the application of radiotherapy, 100% of NF1 patients will ...
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