What is the role of a simultaneous integrated boost in vulvar cancer to the primary and nodes?
Would you do SIB to gross nodes in the pelvis and/or inguinal region? Would you do SIB to the primary unresected tumor?
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What is the highest dose per fraction you would be comfortable using the treat a vulvar GTV?
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2 Answers
Mednet MemberInvited Expert
Radiation Oncology · University of Texas MD Anderson Cancer Center
Answered on
We typically do a SIB at 2 Gy per fraction to the vulvar GTV and nodes and then do a sequential boost to follow (CTV is treated at 1.8 to CTV in 25 fractions). Presumably, the nodes could be safely treated at a higher dose per fraction since there is typically not a critical structure in close proxi...
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Mednet Member
Radiation Oncology · Vanderbilt-Ingram Cancer Center
Answered on
The following is for gross disease:
For vulvar cases, I do SIB for the lymph nodes. 60 Gy in 25 fractions to inguinal LNs (unless close to skin) and pelvic lymph nodes, as tolerated based on bowel constraints. For pelvic lymph nodes medial to lower pelvic vessels and in close proximity to the non-du...
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