What is the role of PD-1 inhibitors in relapsed B-cell ALL?
1 Answers
Mednet Member
Pediatric Hematology/Oncology · The University of Texas MD Anderson Cancer Center
The role of PD-1 inhibitors in pedi is currently being explored in relapsed B-ALL in the study AALL1821. No interim results have been posted.
Primary samples from pediatric patients with relapsed B-ALL were shown to demonstrate marked up-regulation of PD-1 on T-cells, and up-regulation of PD-L1 on th...