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What is the role of radiation treatment of stage IA ALK negative anaplastic large cell lymphoma?

PET/CT/bone marrow biopsy negative for evidence of distant disease. Following 4 cycles of combination chemotherapy with no evidence of progressive disease.
2 Answers
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Radiation Oncology · Duke University Medical Center
Answered on

It would be helpful to know the site of origin. Most stage I ALCL alk neg would be in the skin, in which case RT is the treatment of choice with little role for chemotherapy. Stage I ALCL, other then skin, would be quite rare with no data to guide us, except that we know response to chemotherapy for...

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Medical Oncology · Washington University School of Medicine
Answered on

In patients with T-cell lymphoma, there is no good evidence to consider "short course" chemotherapy and therefore, it has been my practice to consider 6 cycles of chemotherapy for nodal stage IA ALK- ALCL followed by radiation as consolidation.

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