What is the sensitivity of SLNB after neoadjuvant chemotherapy for cN0 patients?
When would you recommend that SLNB be performed prior to neoadjuvant chemotherapy? When would you recommend additional staging (completion axillary dissection)? Would you ever recommend nodal irradiation in these patients [cN0 and ypN0(sn)]?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
The sensitivity of SNLN for clinical N0 disease is high and can be treated like node negative. One has to be cautious about clinical positive patients which normalizes after chemo, as based on ASOCOG and SENTINA trial it can be less than 90% unless due diligence is done like clipping the involved no...
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