What is the significance of grade in OPSCC?

Multiple groups have found an association between the impact of fractionation schedule on outcome and tumor differentiation using high quality prospective data (Eriksen et al., PMID 14751528, Bentzen et al., PMID 16110017, Lyhne et al., PMID 26255764). Well-diff and to a lesser extent moderate-diff ...

They are mostly poorly differentiated. I pay attention to P16 status, not so much grade.