What is the treatment strategy and priority in a patient with newly diagnosed Hodgkin lymphoma but HLH at presentation?

Would be good to have more details about the patient's medical condition and organ function. How definitive is the HLH diagnosis as against Hodgkin's with B symptoms?

Malignancy-associated HLH at diagnosis is due to cytokines/chemokines produced by the tumor cells, so the major part of the therapy is to treat the tumor.

Malignancy HLH can also occur on therapy, but that is thought rather to be associated with immunosuppression and infection. I know Hodgkin alone results in decreased cellular imm...