What is you approach for first line treatment in an elderly patient >85 years of age with good PS and a hairy cell leukemia variant?
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What first line treatment would you use in an elderly patient >85 years old with good PS diagnosed with hairy cell leukemia variant?
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2 Answers
Mednet MemberInvited Expert
Medical Oncology · University of Maryland Cancer Center
Answered on
The 1st question is: does he need treatment? Such as significant cytopenia(s), symptomatic splenomegaly, or constitutional symptoms? If so, and at > 85 yo, I will probably try rituximab alone after discussing with him that this is typically reserved for a relapsed disease, but the alternative is che...
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Mednet Member
Medical Oncology · Joliet Oncology - Hematology Associates, Ltd.
Answered on
If he has a good PS and he needs treatment, Pentostatin Q 2-3 weeks can be considered. Rituxan may be an option too.
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