Topics:
Medical Oncology • Leukemia
What is you approach for first line treatment in an elderly patient >85 years of age with good PS and a hairy cell leukemia variant?
Answer from: Medical Oncologist at Academic Institution
The 1st question is: does he need treatment? Such as significant cytopenia(s), symptomatic splenomegaly, or constitutional symptoms? If so, and at > 85 yo, I will probably try rituximab alone after discussing with him that this is typically reserved for a relapsed disease, but the alternative is ...
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Answer from: Medical Oncologist at Community Practice
If he has a good PS and he needs treatment, Pentostatin Q 2-3 weeks can be considered. Rituxan may be an option too.