What is your adjuvant therapy for node positive, low grade endometrioid endometrial adenocarcinoma?
Answer from: Radiation Oncologist at Academic Institution
Chemotherapy (typically carboplatin/paclitaxel x 6 cycles), restage, and if no progression, whole-pelvic RT. Consider brachytherapy boost if cervical stromal or vaginal involvement and/or presence of other risk factors for vaginal cuff recurrence (e.g. LVSI, deep myometrial invasion, grade 3 [not in...
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Answer from: Radiation Oncologist at Academic Institution
In addition to Dr. @Michael Xiang's option of sequential chemotherapy followed by radiation +/- brachytherapy, there are a few other options that are also very reasonable:1) Concurrent chemoradiation with 2 cycles Cisplatin followed by consolidation chemotherapy - the experimental arms of both GOG 2...
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Radiation Oncologist at Mon Health
I agree wholeheartedly with your last sentence. Th...
I agree wholeheartedly with your last sentence. Th...
at Baptist Medical Group
Perhaps I am confused, but the authors of GOG 258 ...
Perhaps I am confused, but the authors of GOG 258 ...
Answer from: Radiation Oncologist at Community Practice
Currently, most treat with sequential chemotherapy plus EBRT. Although if it is POLE type, then the value of chemotherapy is debatable (PORTEC-3) and that’s why current ESTRO guidelines didn’t come out with specific recommendations for stage III POLE type.