Mednet Logo

What is your antipsychotic of choice and general titration regimen in the outpatient setting for a patient with dementia and behavioral disturbances (assuming reversible causes such as urinary retention, constipation, etc. have been addressed)?

Community PollStarted

What is your antipsychotic of choice and general titration regimen in the outpatient setting for a patient with dementia and behavioral disturbances (assuming reversible causes such as urinary retention, constipation, etc. have been addressed)?

97 physicians have voted

Join Mednetto vote and see how they answered.

3 Answers
Mednet Member
Mednet Member
Geriatric Medicine · Twin Cities Physicians
Answered on

While not set in stone and knowing that there is a black box warning, make sure you get informed consent. I start with low doses of quetiapine (12.5 to 25 mg), as it has the shortest half-life, and will use it twice or 3 times a day. This allows for quicker recovery if they are too sedated. Dependin...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Geriatric Medicine · University of Minnesota
Answered on

All have limited evidence, but aripiprazole, olanzapine, and risperidone generally have the most evidence behind them. (f.e, Maher et al., PMID 21954480). Caveat is brexpiprazole, which has FDA approval for use in Alzheimer's Dementia, in part because it was specifically studied for that purpose.

Sel...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Psychiatry · McLean Hospital/Harvard Medical School
Answered on · Updated on

For antipsychotics in BPSD - I have been following a similar version of this for years with good outcomes.

Chen et al., PMID 33340800

Join for free or sign in to see the full answer