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What is your approach for patients with recurrent nephrolithiasis who require daily use of acetazolamide for management of an unrelated chronic condition?

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Mednet Member
Mednet Member
Nephrology · Mayo Clinic

Acetazolamide, or other carbonic anhydrase inhibitors, typically increase urine pH into the low 7s. Normally, it is approximately 6.0. A mildly alkaline urine favors the formation of brushite and hydroxyapatite kidney stones.

My first step is to contact the provider who prescribed the carbonic anhyd...

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