What is your approach to bridging anticoagulation in patients with history of recent HIT?
Do you always avoid heparin/enoxaparin or rechallenge if antibodies are negative?
Answer from: at Community Practice
One should not re-expose patients with past HIT to heparins. Even with remote HIT, there is a high rate of serologic recurrence (eg, Warkentin and Anderson, PMID 27114458) and while the rate of overt HIT relapse may be low with proper precautions, I have seen and published a couple of fatal HIT recu...
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