What is your approach to checking IgG levels post vaccination to detect common variable immunodeficiency in patients with systemic lupus?
If a deficiency is present, do you consider IVIG to treat non-infectious symptoms such as skin rash, arthritis or hematological abnormalities?
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Do you routinely check post-vaccination titers in SLE patients?
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1 Answer
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Rheumatology · Uniformed Services University of the Health Sciences (USUHS)
Answered on
I recommend that this type of workup for primary immunodeficiency disorders be done as soon as a diagnosis of systemic lupus erythematosus (SLE) is made. In other words, order quantitative immunoglobulins (IgA, IgM, IgG) plus IgG subclasses during your initial workup.
Reasons being:
- Some primary immu...
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