What is your approach to choosing a particular advanced therapy based on patient or disease factors when initiating treatment for moderate-severe IBD?

The selection is based less on relative efficacy and safety (aside from JAKs) and more on the patient: Age, gender, family history, and co-morbidities.

• Younger males: more concern regarding lymphoma with thiopurines.
• Young women: If contemplating pregnancy would consider biologics vs small molecule...