Topics:
Radiation Oncology • Genitourinary Cancers • Bladder Cancer • Medical Oncology • NCI-CCC Tumor Board Question • Vanderbilt • NCI-CCC GU Tumor Board Question
What is your approach to consolidation for localized small cell bladder cancer after neoadjuvant cisplatin and etoposide?
Specifically, for cT2N0M0 small cell bladder cancer without response to neoadjuvant cisplatin and etoposide on imaging, would you proceed with cystectomy?
Answer from: Medical Oncologist at Academic Institution
There is limited data with regard to the best management of these patients. Most data is retrospective and has an inherent bias. That being said, there seems to be a benefit for surgical resection after NAC (Patel et al., 24036236), with RT a consideration if surgery is not an option. In a smal...
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