What is your approach to counseling patients regarding re-initiation of anti-TNF therapy after completion of treatment for non-disseminated pulmonary histoplasmosis?
Would it be safe to resume and if so, when?
Answer from: at Academic Institution
Generally with regards to Histoplasmosis, as with many other infectious diseases, treatment of the infection (either active treatment or completed treatment) is not a contraindication to re-initiation of the immunosuppressive agent. This should always be a clinical decision based on the relative ris...
Sign in or Register to read more
Answer from: at Academic Institution
We published a retrospective study on this topic in 2015 (Vergidis P et al. Clin Infect Dis. 2015 Aug 1;61(3):409-17). We concluded that resumption of TNF-alpha antagonist therapy may be considered in individuals treated for histoplasmosis who have no evidence of residual disease and undetectable Hi...