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What is your approach to discharge planning for a patient with chronic SIADH who is admitted with asymptomatic acute-on-chronic hyponatremia?

How do you establish an acceptable baseline serum sodium? How do you decide between non-pharmacological interventions, such as fluid restriction vs therapies such as salt tablets, urea, vasopressin antagonists, etc.?
1 Answer
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Hospital Medicine · Dartmouth-Hitchcock Medical Center
Answered on

An acceptable baseline serum sodium level in chronic SIADH is based on both clinical status and risk of complications. Based on literature, in the absence of severe symptoms, the target is a gradual correction to a level that minimizes neurocognitive and physical impairment, typically aiming for a s...

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