What is your approach to dosing and duration of rituximab for refractory lupus nephritis not responsive to cyclophosphamide or mycophenolate?

Topics: Rheumatology • Rituximab • Systemic lupus erythematosus

Do you add low-dose mycophenolate to use in combination with Rituximab in these patients?

Answer from: at Community Practice

FirstThe question specifically states "not responsive." It would be highly improbable not to have some improvement with these therapies in conjunction with using hydroxychloroquine (HCQ), steroids, ACE inhibitors, ARBs, and sodium-glucose cotransporter 2 (SGLT2) inhibitors in an adherent patient.Wha...

Comments

at Vanderbilt University School of Medicine
Thoughtful and elegant answer on what is failure. ...

at Uniformed Services University of the Health Sciences (USUHS)
Thanks for this addition, @Erica L. Benvenutti. A...

at University of Nevada - Las Vegas
The other issue that might prompt one to consider ...

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