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What is your approach to extremity STS (G2-3) after an initial unplanned (non-oncologic) surgery who is planned for oncologic re-excision?

When do you offer preop RT (50Gy) before the re-excision? When do you offer post-op RT after the re-excision?
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What would you recommend after non-oncologic surgery for a high grade, high stage sarcoma with a planned re-excision?

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2 Answers
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Radiation Oncology · Fox Chase Cancer Center
Answered on

I, too, usually offer pre-operative radiation therapy in these cases with plans for re-resection by our sarcoma surgeons. I am generally a proponent of neoadjuvant therapy as the volumes are smaller, there is less confusion of the field in need of treatment, the dose is less, and, as I see patients ...

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Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on

With a grade 2-3 STS following a non-oncologic resection, our preference is to consider pre-operative RT. These cases may not have had a pre-operative MRI prior to first resection, so we obtain this and use it to help with treatment planning. However re-resection (with imaging prior) followed by pos...

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