What is your approach to immunotherapy-related pancreatitis?
How do you manage the initial event, including length of steroid taper and the role of pancreatic enzyme monitoring?
What is your experience of subsequent diabetes or other late complications?
Do you consider re-challenge with immunotherapy after resolution?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · University of North Carolina Hospitals, Chapel Hill
Answered on
Depending on the severity of the ICI-associated pancreatitis, I will start patients on prednisone 0.5 mg/kg/day - 1 mg/kg/day. Once lipase levels decrease and approach normal levels, I will start tapering at generally around 10 mg weekly with a total taper time that is typically close to 6 weeks. If...
Join for free or sign in to see the full answer