What is your approach to iron deficiency anemia after negative EGD and colonoscopy-specifically, do you routinely proceed with video capsule endoscopy, or tailor that decision based on patient factors affecting pretest probability?

If there is no sign of atrophic gastritis and repeated fecal tests for blood are negative, I’d look first for celiac disease. If all the celiac screening tests rule it out, then I might team up with a hematologist to look for rare birds like transferrin deficiency. I’d probably ease back on PPIs if ...