What is your approach to IV fluid resuscitation during a sickle cell vaso-occlusive crisis?

How do you reconcile the potential risks and benefits of IV fluids in this patient population? Do you have a preferred type of fluid, as was suggested by a recent study in JAMA Internal Medicine?

Answer from: at Community Practice

My approach to IV fluid resuscitation in vaso-occlusive crisis is cautious and individualized. Adequate hydration is important to prevent further sickling, but I avoid aggressive fluid loading because of the risks of pulmonary edema and acute chest syndrome. I typically use isotonic balanced crystal...

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at Nationwide Children's Hospital
There are ASH Guidelines for IVF in acute pain in ...

at University of Colorado
Thank you both! Very helpful!

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What is your approach to IV fluid resuscitation during a sickle cell vaso-occlusive crisis?

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