What is your approach to IV fluid resuscitation during a sickle cell vaso-occlusive crisis?

My approach to IV fluid resuscitation in vaso-occlusive crisis is cautious and individualized. Adequate hydration is important to prevent further sickling, but I avoid aggressive fluid loading because of the risks of pulmonary edema and acute chest syndrome. I typically use isotonic balanced crystal...

Thank you for this important question. Thank you to all the non-hematologists (internists, hospitalists, ED, family practice) who care for sickle cell adults. In pediatrics, only a pediatric hematologist cares for sickle cell children because this disease is so complex. But I know that there are van...