What is your approach to monitoring for hepatic fibrosis in chronic methotrexate use?

Topics: Rheumatology • General Rheumatology • Dermatology • Systemic autoimmune diseases • RheumMadness

Do you frequently order liver biopsies for these patients?

This question is part of a collaboration with RheumMadness and is specifically in reference to: Methotrexate Liver Toxicity

Answer from: at Academic Institution

Historically, in lower-risk patients (e.g. rheumatoid arthritis patients who are less likely to have metabolic syndrome and are treated with lower doses), guidance has been to proceed with liver biopsy if repeated tests show elevated liver enzymes or hypoalbuminemia. In higher risk patients, (e.g. p...

Comments

at UTMB Health
Historically, dermatologists have routinely ordere...

Related Questions