What is your approach to pancreatic adenocarcinoma s/p surgery with N0/R0 disease and intermediate risk factors with regard to adjuvant chemo-radiation?
How do high risk features like LVI, PNI, or peri-pancreatic fat invasion inform your recommendation?
Answer from: Radiation Oncologist at Academic Institution
With the presentation of RTOG 0848 at ASCO 2024, our practice has changed to offer adjuvant chemoradiation if there is no evidence of distant spread after the completion of any planned adjuvant chemotherapy. Per 0848, we are only offering radiation to patients with tumor of the pancreatic head (body...