What is your approach to re-challenging patients with immune checkpoint inhibitors whom developed predominately acute tubular injury without acute interstitial nephritis?

In patients with immune checkpoint inhibitor (ICI)-associated acute interstitial nephritis (AIN) whose renal function has recovered, most do not develop recurrent ICI-associated AIN after rechallenge. However, data on the recurrence of acute tubular injury (ATI) specifically after ICI rechallenge ar...