What is your approach to Tardive Dyskinesia when VMAT2 inhibitors are ineffective or unaffordable?
Do you consider DBS for severe/refractory cases?
Answer from: at Community Practice
In established cases of tardive dyskinesia, in which withdrawal-emergent dyskinesia has been ruled out, and dyskinesia has persisted despite a sufficient washout interval after removal of the offending agent, VAM2 inhibitors such as valbenazine and deutetrabenazine are used for pharmacotherapy. If t...