What is your approach to using newer atypical antipsychotics in the treatment of schizophrenia?
E.g., Latuda (lurasidone), Fanapt (iloperidone), Vraylar (cariprazine), Rexulti (brexpiprazole), Caplyta (lumateperone), or Saphris (asenapine), Lybalvi (olanzapine/samidorphan)
Are there specific patient factors or indications that would influence you to choose one of these newer antipsychotics? How effective are they in your personal experience?
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Which of the newer atypicals have you ever prescribed for schizophrenia?
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3 Answers
Mednet MemberInvited Expert
Psychiatry · South Broward Hospital District
Answered on · Updated on
- Latuda - great for mood stabilization and bipolar depression. A lot of people like it for borderline personality disorder, but it’s not FDA-approved for that. In my experience, not that great for psychosis or mania, but it also doesn’t really cause weight gain or QTc prolongation. Out of all the se...
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Mednet Member
Psychiatry · Biological Psychiatry Center Pc
Answered on
Cost and affordability.
Access to meds.
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Mednet MemberInvited Expert
Psychiatry · Private Practice
Answered on
While I do not treat many patients who have schizophrenia in my outpatient practice, I do treat a lot of patients who have bipolar disorder. I agree with Dr. @Dr. First Last. I would add that Caplyta (lumateperone) is one of the most weight-neutral of the atypical agents I have used. I have seen wei...
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