What is your approach to VTE prophylaxis in hospitalized patients who are already on DAPT?
Particularly with prolonged hospitalizations, do you have any concerns about exposing patients to bleeding risks associated with "triple therapy" even though dosing for the anticoagulant is prophylactic?
Answer from: at Academic Institution
DAPT by itself is not considered DVT prophylaxis in patients at high risk of DVT. However, LMWH at prophylactic doses can increase the need for transfusions in patients on DAPT, without decreasing VTE rates. In general, I consider patients individually:
Do they still need DAPT? With discontinuity...