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What is your decision process on decreasing the sodium goal for patients with cerebral edema?

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Neurology · University of Pennsylvania
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In my practice, when treating an adult patient with cerebral edema, we avoid hyponatremia but do not set a specific sodium goal. Rather, we titrate therapies (e.g., mannitol, hypertonic saline) to achieve a specific ICP goal (e.g., ICP < 22 mmHg). We stop administering mannitol if the osmolar gap > ...

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