Mednet Logo

What is your management strategy for unresectable endometrial cancer due to gross cervical involvement with parametrial extension?

If the patient is responding to external beam and likely to be converted to resectable, what brachytherapy dose/fractionation do you prescribe and what volume do you cover?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Our approach is PETCT and MRI for staging. Neoadjuvant chemo RT with external beam and brachy to EQ2 dose of 65-70 Gy folllowed by extrafascial hysterectomy and then adjuvant chemotherapy

below is link to our published data

https://www.ncbi.nlm.nih.gov/pubmed/25218303

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Kentucky
Answered on

I am not totally sure of the value of chemotherapy with the pre-operative RT, although I can understand that recommendation. If patients are going to have a major operation following pre-op RT, there is also a downside to it. Just like in cervical cancer with parametrial extension, it could well be ...

Join for free or sign in to see the full answer