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What is your practice regarding giving G-CSF to patients with ALL during initial induction?   

The patient was recently diagnosed with pre-B ALL and is on day 10 of CALGB 10403. He is expectedly neutropenic as he received daunorubicin and vincristine. He is on "adequate" antimicrobial prophylaxis.

ASCO guidelines say nothing about adults or AYA with ALL. The closest I could find was; "CSFs should not be used in pediatric patients with non-relapsed acute lymphoblastic leukemia (ALL) or non-relapsed acute myeloid leukemia (AML) who do not have an infection. (Type: informal consensus. Evidence quality: intermediate. Strength of recommendation: moderate.)".



Answer from: Medical Oncologist at Academic Institution

Answer from: at Academic Institution