What is your practice regarding giving G-CSF to patients with ALL during initial induction?

My colleagues and I do not use G-CSF in either ALL or AML unless the neutropenia is unusual and prolonged and associated with infection.

The use of G-CSF has been shown to shorten neutropenia by a few days but does not prevent the drop and theoretically, at least it may prolong thrombocytopenia by p...

We take a similar approach. We generally reserve G-CSF for treatment of severe neutropenia with fever or documented infection, which is not particularly common with this regimen.

An example of the evidence alluded to by Dr. @Dr. First Last is the CALGB 9111 trial (Larson et al., PMID 9716583). This ...