What is your preferred adjuvant chemotherapy for a pediatric patient less than 1 year old who had a gross total resection of a localized intracranial ependymoma, and will not be receiving radiation therapy due to his/her young age?
1 Answers
Mednet Member
Pediatric Hematology/Oncology · C. S. Mott Children’s Hospital, University of Michigan
Based on the results of the St Jude multi-institutional clinical trial for young children with ependymoma, SJYC07, the results of which were published recently in the neuro-oncology journal, we would recommend systemic therapy with a combination of methotrexate, vincristine, cisplatin and cyclophosp...