Topics:
Radiation Oncology • Thoracic Malignancies
What is your preferred approach for late recurrence at a primary site only of a limited stage small cell lung cancer initially treated with chemoradiaton?
Would you do concurrent vs. sequential chemoradiation? What would be your preferred dose and fractionation?
Answer from: Radiation Oncologist at Academic Institution
"Late" recurrences of small cell lung cancer are unusual. For example, brain metastases very rarely develop after 3 years, and most have developed by 2 (NEJM 1999;341:476). A similar pattern has been observed for local disease (JCO 1997;15:3030). Thus, one must be suspicious when a "late" recurrence...
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