What is your preferred dose for definitive radiation of squamous cell cancer of the thoracic esophagus that will be combined with chemothererapy?

Would your approach change if the histology were adenocarcinoma?

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What is your preferred dose for definitive radiation of squamous cell cancer of the thoracic esophagus that will be combined with chemothererapy?

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1 Answer

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Radiation Oncology · Varian Medical Systems/Allegheny health network

Answered on

We normally plan for 50.4 Gy to 59.4 Gy based on tolerance, realizing the fact that RTOG didn't show a benefit for more than 50.4 Gy. The European studies which compared triple modality to chemo RT delivered dose in 60s and, although they showed feasibility, they did report high stricture rates.

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