Topics:
Head and Neck Cancers • Radiation Oncology
What is your preferred dose-fractionation regimen for cT1-T2N0 oropharynx treated with radiation alone?
Is conventional fractionation acceptable, or would you use altered fractionation (DAHANCA, SIB, BID etc.)?
Answer from: Radiation Oncologist at Community Practice
The results from RTOG 0022 showed very high local control and low salivary toxicity with moderately accelerated hypofractionation SIB.
They gave 2.2 Gy x 30 fractions (66 Gy) to gross disease, and 1.8 Gy (54 Gy) to lower risk areas and achieved <10% LF at 2 years. 7 patients failed, but 2 of the...
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