Mednet Logo

What is your preferred dose-fractionation regimen for cT1-T2N0 oropharynx treated with radiation alone?

Is conventional fractionation acceptable, or would you use altered fractionation (DAHANCA, SIB, BID etc.)?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Michigan Healthcare Professionals, PC
Answered on

The results from RTOG 0022 showed very high local control and low salivary toxicity with moderately accelerated hypofractionation SIB.

They gave 2.2 Gy x 30 fractions (66 Gy) to gross disease, and 1.8 Gy (54 Gy) to lower risk areas and achieved <10% LF at 2 years. 7 patients failed, but 2 of them ha...

Join for free or sign in to see the full answer