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What is your preferred first line management of alcohol use disorder with concomitant depression?

2 Answers
Mednet Member
Mednet Member
Primary Care · Yale

The presence of comorbid depression doesn't significantly change the way I think about pharmacotherapy for AUD. I would still consider disulfiram, naltrexone (PO and IM), and acamprosate as equivalent first-line agents. It's worth noting that distinguishing between major depressive disorder and subs...

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Mednet Member
Mednet Member
Primary Care · Phoenix House New York

I continue to recommend FDA approved AUD treatment options regardless of concomitant depression - offering naltrexone as a first line and acamprosate as a first line alternative and disulfiram (for those interested in complete abstinence and have someone who can help assist in accountability for dai...

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