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What is your preferred first line systemic treatment for recurrent, metastatic, low grade, ER/PR+ pMMR endometrioid endometrial carcinoma?

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What is your preferred first line systemic treatment for recurrent, metastatic, low grade, ER/PR+ pMMR endometrioid endometrial carcinoma?

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3 Answers
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Gynecologic Oncology · Vanderbilt University School of Medicine
Answered on

Given the data presented at the most recent SGO Annual Meeting on Women's Cancer, published simultaneously in the New England Journal of Medicine, and recently endorsed by the National Comprehensive Cancer Network (NCCN), the standard of care for recurrent endometrial cancer, regardless of MMR statu...

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Medical Oncology · NYU Langone Medical Center
Answered on

I have had a few patients with metastases (ER +) after long disease free intervals (> 10 years) who have responded very well and durably to hormonal therapy with few side effects (which include cost, etc). So I think there may still be a role for hormonal therapy in the appropriate setting (Long DFI...

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Gynecologic Oncology · ProMedica Toledo Hospital
Answered on

Can always use cytotoxic therapy if hormonal fails.

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