Topics:
Sarcoma • Medical Oncology
What is your preferred first-line therapy for metastatic extraskeletal osteosarcoma in a young, fit patient?
AIM or doxorubicin/cisplatin? Would you recommend adding methotrexate?
Answer from: Medical Oncologist at Academic Institution
EOS behaves more like a soft-tissue sarcoma c.f. skeletal OS, so we treat with anthracycline plus Ifosfamide. Cisplatin and HD MTX routinely used for skeletal OS do not have significant activity in EOS.
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