What is your preferred formulation of parenteral iron?

Topics: Pediatric Oncology • Medical Oncology • Hematology • Pediatric Hematology • Benign Hematology

There are various formulations of intravenous iron; each with varying costs, test dose requirement, elemental dose, and number or time of infusions needed. How do you approach selecting the optimal formulation of intravenous iron and/or do you prefer certain ones in specific clinical scenarios (e.g. heart failure, CKD, pregnancy etc.)?

Answer from: Medical Oncologist at Academic Institution

The question is not simple. The formulation I use the most is ferumoxytol because four insurance carriers allow a total dose infusion of 1020 mg in 20-30 minutes. This has been published twice (Auerbach et al., PMID 21922526 and Karki and Auerbach, PMID 31155744). Otherwise, it must be given as two ...

Comments

Medical Oncologist at Rush University Medical Center
In a patient who develops a severe infusion reacti...

Medical Oncologist at Georgetown University School of Medicine
I would never use iron sucrose. I would premedicat...

Medical Oncologist at Rush University Medical Center
Thank you, Dr. @Auerbach.

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