What is your preferred second-line treatment for high-grade neuroendocrine carcinoma of GI origin after progression on carboplatin + etoposide?
For this example, Ki-67 of 80, MSS, low TMB
Answer from: Medical Oncologist at Community Practice
This is a great question. I will try to summarize the current data for treating poorly differentiated GEP-NEC.
However, high-grade poorly differentiated GEP neuroendocrine carcinomas (GEP-NECs) are rare cancers, there is an increase in incidence estimated to be 0.2-0.5 per 100,000 inhabitants). (1-...
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