What is your preferred stain for melanocytic lesions?
SOX-10, MITF, PRAME, S100, etc?
Answer from: at Academic Institution
Our lab uses all the listed stains. Which one(s) depends on context + question. Results will inevitably vary between labs. Currently, PRAME and SOX-10 are our two most popular.
Nevus vs melanoma. PRAME, as an ancillary diagnostic test.
Definitive confirmation of melanocytes (vs non-melanocytes) ...