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What is your re-immunization strategy after auto SCT for patients with myeloma on dara/len maintenance?
Prior guidance was mostly derived in the era of len maintenance +/- adding a PI for high-risk patients. Do you avoid live vaccines?
Answer from: Medical Oncologist at Community Practice
We do the same vaccination sequence according to BMT/CTN, whether they are on maintenance dara or not. Here is our schedule
Post autologous SCT vaccine
Interval Date Vaccine
Yearly Flu Vaccine
3-month post-transplant Pneumovax 20, Hib, hep A/hep B, polio, TDap, Shingrix
6 months post-transplant...
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Answer from: Medical Oncologist at Community Practice
The BMT/CTN schedule has not been re-examined, unfortunately. Hib & polio are thankfully not a risk in the U.S. for now, and so these vaccinations do not have an appealing benefit:risk ratio - similar to MenACWY, MenB, and HPV.
Hepatitis A and B have individualized risk factors per the previous...