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What is your recommended management for a pT1N0 perianal moderately differentiated SCC s/p wide local excision with close 1 mm deep margin?

Not a candidate for re-excision given proximity to the anal sphincter. Consider +PNI, -LVI.
1 Answer
Mednet Member
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Radiation Oncology · Washington University School of Medicine
Answered on

It’s important to examine the patient before proceeding. Anal and peri-anal cancer can be multi-centric. I have had cases with pathology reports like this who had other areas of clearly invasive disease remaining.

Assuming staging studies are negative and the physical examination reveals only a hea...

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