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What is your standard for monitoring triglyceride level during therapy for ALL, particularly in regards to receiving pegaspargase?

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When do you check triglyceride levels in a patient with ALL receiving pegaspargase?

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1 Answer
Mednet MemberInvited Expert
Medical Oncology · City of Hope Comprehensive Cancer Center
Answered on

Routine monitoring of triglyceride levels is not considered standard practice during pegaspargase therapy. Although hypertriglyceridemia is a common side effect of asparaginase treatment, it typically has no significant clinical impact on management decisions or future use of asparaginase. The condition is usually self-limited, and available experiences have not demonstrated a correlation between hypertriglyceridemia and an increased risk of pancreatitis during asparaginase therapy. In cases of ...

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